1. extenuate

1. Nothing can extenuate his crime.
    他的罪责无法减轻。；他的罪责无法用任何辩解减轻。

2. Nothing can extenuate his guilt.
    他的罪无法减轻。

1. 减轻：extend 延长 | extenuate 减轻 | exterior 外在的; 外面,外表

2. 使(罪过等)显得轻微：exhume#从墓中掘出 | extenuate#使(罪过等)显得轻微 | extol#颂扬

3. extenuate

3. 掩饰(罪行),减轻罪过：extant 现存的,传世的 | extemporize 即席演说 | extenuate 掩饰(罪行),减轻罪过

4. extenuate

4. 低估：extenttable 范围表 | extenuate 低估 | extenuation 低估

1. It is in vain, sir, to extenuate the matter.
    先生，大事化小的做法是无济于事的。

2. His Majesty gave many marks of his great lenity, often... endeavoring to extenuate your crimes.
    国王陛下多次表示了他的仁慈，常常…试图减轻你的罪行。

3. His Majesty gave many marks of his great lenity, often. endeavoring to extenuate your crimesJonathan Swift.
    国王陛下多次表示了他的仁慈，常常…试图减轻你的罪行。

4.

4. Nothing can extenuate his guilt.
    他的罪无法减轻。

5. extenuate

5. Nothing can extenuate his base conduct.
    他的卑鄙行为无可掩饰。

6. During the period of the people's procuratorate'examining of the prosecution or after it institutes a prosecution, if the defending lawyer finds any evidential materials that can prove the innocence or light offence of the suspected criminal or can extenuate or exempt him from punishment, and provide these evidential materials to the people's procuratorate, the public prosecution department of the people's procuratorate shall accept and examine them.
    在人民检察院审查起诉期间和提起公诉以后，辩护律师发现犯罪嫌疑人无罪、罪轻、减轻或者免除处罚的证据材料向人民检察院提供的，人民检察院公诉部门应当接受并进行审查。

7. Nothing can extenuate such cruelty.
    如此残忍不可原谅。

8. Results:1MTT assay shows that exogenous H_2O_2 induces decreasing of cell viability of H9C2 cells in a dose-dependent manner(P＜0.05), and 100μM H_2O_2 treating for 4 hours was chosen as inducing condition for the following experiments. Various concentrations of E_2 alone has no effect on the cell viability of H9c2 cells(P＞0.05).Exogenous H_2O_2 increasing the apoptosis rate and ROS generation. While H9c2 cells pretreated with 200nM E_2 for 24 hours significantly attenuate the cell viability injury caused by H_2O_2.Time-phase analysis shows that the maximal protective effect achieved at 16 hours, and last for 24 hours. E_2 inhibited the cell viability injury caused by H_2O_2 in a dose dependent manner. So we choose 200nM E_2 treating for 24 hours as the intervention treatment in the follow experiment.2Exogenous H_2O_2 may induce increased apoptosis and ROS generation of H9c2 cells, there is a significant difference compared with control group. E_2 pretreatment can significantly extenuate apoptosis and ROS generation of H9C2 cells induced by H_2O_2(P＜0.05).3Determination of estradiol receptor expression of H9C2 cells by RT-PCR finds that H9C2 cells only express ERβ, almost express no ERα, and suggests that anti-apoptosis effect of estradiol on H9C2 cells may be mediated by ERβ.4Detection of Realtime RT-PCR and western blot finds that H9C2 cells pretreated by estradiol for 8 hours may downregulate the expression of TβRⅠand TβRⅡmRNA, and downregulate of protein expression occurred at 16 hours. But it has no effect on the expression of TGF-β1.ER blocker ICI182, 780 can block the binding of E_2 and ER, and can delete the downregulation effect of E_2 on TβRⅠand TβRⅡ.5Western blot exanmination shows that the p-smad2/3 level in H9c2 cells decreased pretreated by estradiol for 16 hours H9c2 cells.
    结果：1MTT分析显示外源性H_2O_2呈浓度依赖性诱导H9c2细胞活性下降(P＜0.05)，选择100μM H_2O_2处理4小时作为后续试验的诱导条件；单纯应用不同浓度E2(50-200nM)处理H9c2细胞对其活性均无明显影响P＞0.05应用200nM E2预处理H9c2细胞24小时可明显减轻H_2O_2对H9c2细胞活性的损伤(P＜0.05，时相效应分析显示保护作用16小时达高峰可持续至24小时；应用不同浓度E_2(50-200nM)预处理24小时，E_2呈浓度依赖性抑制H_2O_2对H9c2细胞活性的损伤；依此结果选择200nM E2预处理24小时作为后续实验的干预条件。2应用流式细胞仪检测H_2O_2诱导的H9c2细胞凋亡、ROS生成及E2的干预作用，结果显示，外源性H_2O_2可引起H9c2细胞凋亡及ROS生成明显增加，与对照组比较差异明显P＜0.05E_2预处理能够明显减轻H_2O_2诱导的H9c2细胞凋亡，差异具有显著性(P＜0.05.3RT-PCR鉴定H9c2细胞ERα和ERβ的表达情况，发现H9c2细胞仅表达ERβ，几乎不表达ERα，推测E2对H9c2细胞的抗凋亡保护作用可能是通过ERβ介导。4Realtime RT-PCR以及Western blot检测结果显示应用200nM E2处理H9c2细胞8小时后可下调TβRⅠ以及TβRⅡmRNA的表达，处理16小时后下调TβRⅠ以及TβRⅡ蛋白表达，但是对于TGF-β1mRNA及蛋白表达均无明显影响，给予ER阻断剂ICI 182，780阻断E_2与ER的结合，能够消除E2对TβRI及TβRⅡmRNA的下调作用。5Western blot检测p-smad2/3蛋白水平显示，E2处理16小时后p-smad2/3蛋白水平降低。

9. extenuate

9. N It is in vain, sir, to extenuate the matter.
    n 先生们，掩盖局势的严重性是无济于事的。

10. I write the exact truth. It would avail me nothing to extenuate it now
    我所写的都是事实，我现在想为自己开脱，也丝毫无济于事。

11. And in the design of the additional layer of the noise-damping tower, the light-weight steel framework, the light-weight wall body and the rubber isolating layer are adopted to extenuate the shaking.
      在加层设计中，有效地运用了轻钢结构体系、轻质墙体和橡胶垫隔震层来减轻震动的作用。

12. Nothing can extenuate such appalling behavior.
      这种骇人听闻的行径罪不可恕。

13. He thought it necessary to extenuate the length of time he kept the dinner on the table.
      他认为必须解释一下为何把晚餐留在桌上那么久。

14. Conclusion Emodin can reduce the inflammatory response and extenuate the damage to intestinal mucosa in abdominal infection of rats.
      结论：大黄素能减轻CLP所致腹腔感染大鼠的炎症反应和肠粘膜的损伤。

15. extenuate

15. EA could extenuate cellular edema and mitochondrial swelling in ischemic rats.
      电针治疗还可减轻脑缺血后细胞水肿及线粒体肿胀程度。

16. Extenuate civic " Hot - island effect ";
      减轻城市热岛效应；

17. It might extenuate the heart and lung injury by hypothermia and ischemia reperfusion during cardiopulmonary bypass. Cardiac conducting block might be prevented during operation.
      结论浅低温体外循环心脏跳动中心内直视手术技术安全可行，可有效减轻低温和缺血再灌注对心肺等脏器的损伤作用，有利于避免术中心脏传导阻滞的发生。

18.

18. After oral administration, BPs significantly improved pathological injury. Inflammation were reduced, alveolar hemorrhage were extenuate, alveolar wall and inflammatory cell infiltration were decreased.
      口服给药后，柴胡明显改善了病理损伤，病理切片显示给药后炎症程度明显减轻，肺泡腔出血明显减少，肺泡壁变薄，炎性细胞浸润减少。

19. Conclusion Integrated Chinese and Western medicine treatment of mesangial proliferative glomerulonephritis could extenuate markedly the recurrence rate of disease and the sideeffect of prednisone.
      结论中西医结合治疗激素敏感型系膜增生性肾炎，可以明显减少复发率及强的松的副作用。

20. Tongue and pulse: light tongue texture, fat tongue body or with teeth imprints, thin and white tongue moss and extenuate pulse.
      舌脉：舌质淡，舌体胖或有齿印，苔薄白，脉细弱或弦细。

1. lessen or to try to lessen the seriousness or extent of

    e.g. The circumstances extenuate the crime

    Synonym: palliate mitigate